| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum
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| Autores: |
Del-Vechio-Vieira,Glauciemar
Sousa,Orlando Vieira de
Miranda,Mariza Abreu
Senna-Valle,Luci
Kaplan,Maria Auxiliadora Coelho
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| Data: |
2009-10-01
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| Ano: |
2009
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| Palavras-chave: |
Ageratum fastigiatum
Essential oil
Nociception
Inflammation
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| Resumo: |
The chemical composition, analgesic and anti-inflammatory properties of essential oil from Ageratum fastigiatum were investigated. The main compounds found in the essential oil were germacrene D, α-humulene and β-cedrene. The oil, with LD50 of 2.50 g/kg, inhibited the acetic acid-induced writhing at the dose of 200 mg/kg. In the formalin test, the oil inhibited the first phase (200 mg/kg) and the second phase (100 mg/kg and 200 mg/kg). In the hot plate test, after 30 and 60 min of treatment the doses of 100 and 200 mg/kg increased the reaction time. The antiedematogenic effect, reduction on the exudate volume and leukocyte mobilization were observed at the doses of 100 and 200 mg/kg. The results indicated that A. fastigiatum possessed the analgesic and anti-inflammatory properties that supported the popular medicinal use of the plant.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000500008
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132009000500008
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.52 n.5 2009
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| Direitos: |
info:eu-repo/semantics/openAccess
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